منابع مشابه
Rossi Et Al. Delayed Alternation Prefrontal Cortical Mechanisms Underlying Delayed Alternation in Mice Abbreviated Title: Delayed Alternation 2
34 The prefrontal cortex (PFC) has been implicated in the maintenance of task-relevant information 35 during goal-directed behavior. Using a combination of lesions, local inactivation, and 36 optogenetics, we investigated the functional role of the medial prefrontal cortex (mPFC) in mice 37 using a novel operant delayed alternation task. Task difficulty was manipulated by changing the 38 durati...
متن کاملDelayed Alternation 1 Running head: DELAYED ALTERNATION Prefrontal contributions to delayed spatial and object alternation: A PET study
Delayed alternation tasks are frequently employed as probes of frontal lobe functioning. In order to clarify the neural substrates of delayed alternation performance in humans, we measured regional cerebral blood flow with H20 PET in healthy subjects as they performed delayed spatial and object alternation. Consistent with the monkey lesion literature, increased dorsolateral prefrontal activity...
متن کاملDelayed alternation in honeybees (Apis mellifera).
Previous experiments with honeybees (Apis mellifera) failed to show learned control of performance by short-ten memory. In this study, honeybees were trained with an improved technique to choose 1 of 2 colors that was either the same as a recently rewarded sample (perseveration) or different (alteration). Because any increase in associative strength stemming from the sample experience would ten...
متن کاملThalamic unit activity and delayed alternation performance in the monkey.
Single unit activity was recorded from the thalamus of rhesus monkeys while they performed a delayed-alternation bar-pressing task. Nine units in the dorsomedial nucleus of the thalamus were activated prior to the lever presses of the contralateral hand, as indicated by an EMG of the triceps brachii muscle. In this same region, no units were found that became active during the delay period. In ...
متن کاملHippocampal electrical activity in the monkey during delayed alternation problems.
.... 1 I .. , A well known effect of lesions of frontal granular cortex and of all limbic structures including the hippocampus is the impairment of the classical delayed spatial alternation problem (Pribram et at. 1952. 1962, 1966; Mishkin and Pribram 1955; Mishkin 1964; McEnaney and Butter 1969). Not every alternation performance, however. shows a decrement from frontal cortex or medial forebr...
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ژورنال
عنوان ژورنال: Journal of the Experimental Analysis of Behavior
سال: 1962
ISSN: 0022-5002
DOI: 10.1901/jeab.1962.5-225